PRINCIPAL BLOOD CHANGES
Sr.No. | Blood | Non Pregnant | Pregnancy near term | Change |
I | (1) Blood Volume (ml) | 4000 | 5500 | +30-40% |
(2) Plasma Volume (ml) | 2500 | 3750 | +40-50% | |
(3) Red Cell Volume (ml) | 1400 | 1650 | +18-20% | |
(4) Total Hb (gm) | 475 | 560 | +18-20% | |
(5) Haematocrit (whole body) | 38% | 32% | diminished | |
II | Leucocytes | | | |
(1) Neutrophilic leucocytes | 7,500-10,000 cm | 10,000-15,000 cm - 20,000 /cmm | | |
III | Plasma Protein | | | |
(1) Total Proteins | 180 | 230 | | |
(2) Plasma protein concentration (gm/100ml) | 7 | 6 | ¯ | |
(3) Albumin (gm/100ml) | 4.3 | 3 | ¯ | |
(4) Globulin (gm/100ml) | 2.7 | 3 | Slight | |
(5) Albumin : Globulin | 1.7:1 | 1:1 | ¯ | |
IV | Blood coagulation factors | | | |
| (1) Platelets (/cmm) | 18,00,000 | Controversial observation | Static or 15% reduction of the count |
(2) Fibrinogen (mg%) | 200-400 | 300-500 | +50% | |
(3) Fibrinolytic activity | - | Depressed | - | |
(4) Clotting time | - | Unaffected | - | |
(5) ESR | 10mm/hr | 40mm/hr | Marked (4 times) | |
V. | Blood Lipids (mg/100ml) | | | |
(1) Total lipids | 650 | 1000 | +50% | |
(2) Cholesterol | 180 | 260 | +40% | |
(3) Phospholipids | 250 | 350 | +40% | |
VI | Haemodynamic changes | | | |
(1) Cardiac output (lit/min) | 4.5 | 6.26 | +30% | |
(2) Stroke volume (ml) | 65 | 75 | | |
(3) Pulse rate (/min) | 70 | 85 | | |
(4) Blood pressure | - | Unaffected mid pregnancy drop of diastolic pressure | - | |
(5) Venous pressure (femoral) (cm water) | 8-10 | 20 | +100% | |
(6) Peripheral resistance | | ¯¯ | | |
(7) Blood viscosity (relative to water) | 4.7 | 3.8 | Diminished |